When NASA Administrator Jared Isaacman announced the revamped approach to the Artemis moon program, it was unclear whether the new mobile launcher that has been constructed over the last two years at ...
Deep mutational scanning reveals pharmacologically relevant insights into TYK2 signaling and disease
This important paper presents a rigorous and comprehensive deep mutational analysis of the kinase TYK2, revealing how single amino acid substitutions influence protein abundance, signaling activity, ...
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