The authors do not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and have disclosed no relevant affiliations beyond their ...

Human cancers are thought to be sustained in their growth by a pathologic counterpart of normal adult stem cells: cancer stem cells. This concept was first developed in human myeloid leukemias and is ...

Mathematical models can be useful to developmental biologists, in particular in helping to bridge the gap in understanding between proposed molecular interactions inside and between cells and their ...

Historically, mathematical models in ecology have been used largely to provide qualitative explanations for patterns in nature. A classic example of this approach was the effort to use competition ...