Researchers with the global Human Cell Atlas (HCA) consortium report significant progress in their quest for a better understanding of the cells of the human body in health and disease, with the ...

A time-resolved proteomic atlas of plasma, saliva and urine reveals that a single bout of exercise regulates more than 3,000 ...

In conventional pathology and physiology research, two-dimensional (2D) analysis—observing thinly sliced tissue sections—has been mainstream, making it difficult to comprehensively understand the ...

To understand biomolecules in context, researchers need to know where they are expressed and what they do in healthy tissues. But with roughly 37 trillion cells in a healthy human body, that knowledge ...

The human body contains an astonishing 36 to 37 trillion cells, each serving unique functions across organs and systems. In a groundbreaking initiative, the Human Cell Atlas (HCA), an international ...

High transparency was achieved by optimizing the duration and procedures for delipidation and refractive index matching. (A) Tissue clearing of 11 organs from an adult mouse. (B) Whole-body tissue ...

An aging atlas of 7 million cells reveals that age-related changes in cells are synchronized across organs, suggesting common molecular signals that could be targeted with drugs. As we age with each ...

A new artificial intelligence (AI) tool has mapped how obesity affects the entire body at the cellular level, revealing widespread damage far beyond fat tissue. The study, published in Nature, was led ...